Search Thermo Fisher Scientific. Suchen in Alle. Kundenspezifische Produkte und Dienstleistungen. Katalognummer: A Technischer Support Kundendienst. Ihr Preis Anmelden. This version of the assay is for manual library preparation.
Leveraging the power of Ion AmpliSeq technology, this highly multiplexed NGS assay enables the generation of results from multiple samples in a single run. Samples can be processed quickly and easily, and variants detected and identified confidently in either germline or somatic DNA analysis pipelines.
BRCA mutations resulting in the deficiency of either gene have been shown to result in inefficient activation of this function and are linked to hereditary predisposition to cancer. Figure 3. Superior accuracy in detecting somatic and germline variants that is highly consistent and independent of workflow.
Figure 4. Relative abundance of BRCA exons are plotted. The sample has a deletion in BRCA1 red of exons 4—9 green circle. The green plot indicates the sample ID amplicons used for normalization.
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