You will know basic techniques for integrating and interpreting multi-omics datasets. He has been developing computational methods for analyzing and integrating large-scale genomics data sets since He has published an extensive body of work in this area.
The framework for this book grew out of the yearly computational genomics courses he has been organizing and teaching since The carrot genome was sequenced in , and its relatively small diploid genome, combined with the fact that it is the most complete root crop genome released to date and the first-ever Euasterid II genome to be sequenced, mean the carrot has an important role in the study of plant development and evolution.
In addition, the carrot is among the top ten vegetables grown worldwide, and the abundant orange provitamin A carotenoids that account for its familiar orange color make it the richest crop source of vitamin A in the US diet, and in much of the world.
This book includes the latest genetic maps, genetic tools and resources, and covers advances in genetic engineering that are relevant for plant breeders and biologists alike. This book is the first comprehensive volume on conifers detailing their genomes, variations, and evolution. The book begins with general information about conifers such as taxonomy, geography, reproduction, life history, and social and economic importance. Then topics discussed include the full genome sequence, complex traits, phenotypic and genetic variations, landscape genomics, and forest health and conservation.
This book also synthesizes the research included to provide a bigger picture and suggest an evolutionary trajectory. As a large plant family, conifers are an important part of economic botany. The group includes the pines, spruces, firs, larches, yews, junipers, cedars, cypresses, and sequoias.
Of the phylum Coniferophyta, conifers typically bear cones and evergreen leaves. Recently, there has been much data available in conifer genomics with the publication of several crop and non-crop genome sequences. In addition to their economic importance, conifers are an important habitat for humans and animals, especially in developing parts of the world. The application of genomics for improving the productivity of conifer crops holds great promise to help provide resources for the most needy in the world.
This open access book offers the first comprehensive account of the pan-genome concept and its manifold implications. The realization that the genetic repertoire of a biological species always encompasses more than the genome of each individual is one of the earliest examples of big data in biology that opened biology to the unbounded.
The study of genetic variation observed within a species challenges existing views and has profound consequences for our understanding of the fundamental mechanisms underpinning bacterial biology and evolution. The underlying rationale extends well beyond the initial prokaryotic focus to all kingdoms of life and evolves into similar concepts for metagenomes, phenomes and epigenomes.
The books respective chapters address a range of topics, from the serendipitous emergence of the pan-genome concept and its impacts on the fields of microbiology, vaccinology and antimicrobial resistance, to the study of microbial communities, bioinformatic applications and mathematical models that tie in with complex systems and economic theory. Given its scope, the book will appeal to a broad readership interested in population dynamics, evolutionary biology and genomics.
This text provides a new approach to the subject of genomes and redefines how molecular genetics should be taught. Covering all aspects, it includes key research findings and focuses on the changes of the last five years. This book tells the story behind the first Spirodela genome sequencing project. Further, it describes the current genomics applications of these findings, and efforts to sequence new genomes within the family.
The closing chapters address the sequencing of the over 1 Gigabase Wolffia genomes, which could have major impacts on genome evolution and agricultural research. The duckweed or Lemnaceae family is a collection of 5 genera and 37 species of the smallest, fastest-growing flowering plants. Many of these aquatic monocotyledonous plants can grow all over the world, in a variety of climates. Given their simplified and neotenous morphology, duckweeds have been researched for several decades as a model species for plant physiology and ecotoxicological research, contributing to our understanding e.
In addition, duckweed-based treatment has been a favorite and feasible means, especially in developing countries, of removing phosphorus and pharmaceutical chemicals from sewage and wastewater.
With a dry annual mass yield per hectare of up to 80 tonnes equivalent to 10 tonnes of protein , duckweed is also a promising aquatic crop in new modern and sustainable agriculture.
Besides being an excellent primary or supplemental feedstock for the production of livestock and fish, duckweed biomass can be utilized as a potential resource for human nutrition, biofuel, or bioplastics, depending on water quality as well as protein or starch accumulating procedures. These academic and commercial interests have led to international efforts to sequence the Spirodela polyrhiza genome, the smallest and most ancient genome in the family.
There is growing enthusiasm in the scientific community about the prospect of mapping and sequencing the human genome, a monumental project that will have far-reaching consequences for medicine, biology, technology, and other fields. But how will such an effort be organized and funded? How will we develop the new technologies that are needed?
What new legal, social, and ethical questions will be raised? Mapping and Sequencing the Human Genome is a blueprint for this proposed project. The authors offer a highly readable explanation of the technical aspects of genetic mapping and sequencing, and they recommend specific interim and long-range research goals, organizational strategies, and funding levels.
They also outline some of the legal and social questions that might arise and urge their early consideration by policymakers. This book describes the historical importance of potato Solanum tuberosum L. It also discusses strategies and tools for high-throughput sequencing, sequence assembly, annotation, analysis, repetitive sequences and genotyping-by-sequencing approaches.
Potato Solanum tuberosum L. It is an autotetraploid crop with complex genetics, acute inbreeding depression and a highly heterozygous nature.
Author : Terence A. Updated to incorporate the recent major advances, Genomes 3 is an invaluable companion for any undergraduate throughout their studies in molecular genetics. Genomes 3 builds on the achievements of the previous two editions by putting genomes, rather than genes, at the centre of molecular genetics teaching.
Recognizing that molecular biology research was being driven more by genome sequencing and functional analysis than by research into genes, this approach has gathered momentum in recent years. Author : T. It is a thoroughly modern textbook about genomes and how they are investigated. As with Genomes 3, techniques come first, then genome anatomies, followed by genome function, and finally genome evolution. The genomes of all types of organism are covered: viruses, bacteria, fungi, plants, and animals including humans and other hominids.
Genome sequencing and assembly methods have been thoroughly revised including a survey of four genome projects: human, Neanderthal, giant panda, and barley.
The knowledge gained from these techniques forms the basis of the three chapters that describe the three main types of genomes: eukaryotic, prokaryotic including eukaryotic organelles , and viral including mobile genetic elements. Coverage of genome expression and replication is truly genomic, concentrating on the genome-wide implications of DNA packaging, epigenome modifications, DNA-binding proteins, non-coding RNAs, regulatory genome sequences, and protein-protein interactions.
Also included are applications of transcriptome analysis, metabolomics, and systems biology. The final chapter is on genome evolution, focusing on the evolution of the epigenome, using genomics to study human evolution, and using population genomics to advance plant breeding. Established methods of molecular biology are included if they are still relevant today and there is always an explanation as to why the method is still important.
Topics also include major DNA repair mechanisms, the role of chromatin in genome stability, human diseases associated with genome instability, and genome stability in response to aging. This volume is an essential resource for geneticists, epigeneticists, and molecular biologists who are looking to gain a deeper understanding of this rapidly expanding field, and can also be of great use to advanced students who are looking to gain additional expertise in genome stability.
Author : Jr. Brown, Jr. Author : Michael J. It provides a fully comprehensive review of the field in an easy to search structure. Under the collective leadership of fifteen distinguished section editors, it is comprised of articles written by leading experts in the field, providing a full review of the current status of each topic.
The articles are up-to-date and fully illustrated with in-text references that allow readers to easily access primary literature.
While all entries are authoritative and valuable to those with advanced understanding of evolutionary biology, they are also intended to be accessible to both advanced undergraduate and graduate students. Posted in Ebooks. Search for:.
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